L-Glutamine 500 Grams Pure Grade Value Nutrition L-Glutamine is l-glutamine powder which comes in an economical 500 gram bottle.
Color: white
Physical form: Crystalline powder crystals
The amino acid, Glutamine, has become more prominent as new studies reveal its unique contribution to protein synthesis (muscle growth), anti-proteolytic (prevents muscle tissue breakdown) functions and growth hormone elevating effects.
Glutamine is the most abundant single amino acid in the blood and in the intracellular free amino acid pool (most abundant amino acid in muscle tissue). It comprises 61% of the amino acid pool in skeletal muscle. Glutamine's unique structure, containing two nitrogen side chains, consists of 19% nitrogen - making it the primary transporter of nitrogen into the muscle cell. In fact, glutamine alone is responsible for 35% of the nitrogen that gets into the muscle cell. Glutamine literally drives muscle building nitrogen into the muscle cell where it is synthesized for growth.
Glutamine concentrations fall markedly after training and remain low until complete recovery. What this means is, the very rigors of weight training leak nitrogen carrying glutamine from muscle tissue. This fall in glutamine is catabolic to muscle tissue. Supplementing with glutamine spares free glutamine in muscle tissue, counteracts the fall in muscle protein synthesis, and improves nitrogen balance.
Physiology and Clinical Effects
Glutamine is the most abundant amino acid (protein building block) in the body and is involved in more metabolic processes than any other amino acid. Glutamine is converted to glucose when more glucose is required by the body as an energy source. It serves as a source of fuel for cells lining the intestines. Without it, these cells waste away. It is also used by white blood cells and is important for immune function.
In animal research, glutamine has anti-inflammatory effects. Glutamine in combination with N-acetyl cysteine promotes the synthesis of glutathione, a naturally occurring antioxidant that is believed to be protective in people with HIV infection.1 Evidence indicates that IV glutamine supplementation increases the survival rate of critically ill people.2
Food Sources
Glutamine is found in many foods high in protein, such as fish, meat, beans, and dairy products.
Risk Factors and Symptoms of Deficiency
Few healthy people are glutamine deficient, in part because the body makes its own. During fasting, starvation, cirrhosis, critical illnesses in general, and weight loss associated with AIDS and cancer, however, deficiencies often develop.
Recommended Dosage
Healthy people do not need to supplement with glutamine. A physician should be consulted for the supplemental use of glutamine for the support of serious health conditions.
Contraindications
No significant side effects have been reported in glutamine studies.
Are there any drug interactions?
Certain medicines may interact with glutamine.
Glutamine
Drug Interactions
Certain medicines interact with glutamine: Some interactions may increase the need for glutamine
Note: the following list only includes the generic or class name of a medicine—to find a specific brand name, use the Safetychecker index.
Chemotherapy
Cisplatin
Cyclophosphamide
Docetaxel
Fluorouracil
Methotrexate
Paclitaxel
1. Robinson MK, Hong RW, Wilmore DW. Glutathione deficiency and HIV infection. Lancet 1992;339:1603-4.
2. Griffiths RD. Outcome of critically ill patients after supplementation with glutamine. Nutrition 1997;13:752-4.
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