DescriptionCardiAll is designed to optimize healthy heart and blood vessel function.
The cardiovascular system is a complex and sophisticated network. After all, it must work
non-stop, 24-hours a day for an average of 77.1 years. Even if we eat a healthy balanced diet,
we often do not get the necessary levels of antioxidant nutrients that protect cells from
harmful free radicals, neutralizing these molecular marauders.* Antioxidants protect our
genetic DNA, cellular membranes, and even the enzyme systems that run our cells' metabolism.*
This is why it's critical that we take a quality cardio-protective supplement with key
antioxidants every day.
CardiAll is designed to optimize healthy heart and blood vessel function.
Ingredients (per serving)
CoEnzyme Q10 30 mg
L-Carnitine 100 mg
Hawthorn leaf & flower Extract (1.8% Vitexin) 100 mg
Natural Vitamin E (as d-alpha tocopheryl succinate) 200 IU
Folic Acid 800 mcg
Vitamin B6 (as Pyridoxine Hcl) 30 mg
Vitamin B12 (as Cyanocobalamin) 250 mcg
Betaine (as Tri-methyl glycine) 10 mg
Thiamine (Vitamin B1) (as Thiamine Hcl) 3 mg
Riboflavin (B2) 3.4 mg
Niacin (B3)(as Inositol HexaNiacinate) (flush-free) 40 mg
Magnesium (as Magnesium Arginate) 25 mg
Taurine 100 mg
Vitamin A (as natural mixed carotenoids from Dunaliella) 5000 IU
Vitamin C (as Ascorbic Acid) 120 mg
Zinc (as Zinc amino acid chelate) 15 mg
Selenium (as Selenomethionate) 100 mcg
Chromium (as Chromium Niacinate) 200 mcg
Turmeric root extract (95%Curcumin) 10 mg
CoEnzyme Q10: The Miracle Nutrient For The Heart
CoQ10 is a naturally occurring metabolic enzyme which has been heavily researched for
cardiovascular health. More than 100 clinical studies at major universities and hospitals have
documented the actions of CoQ10. It maintains the strength of the heart muscle more than any
other nutrient.* Virtually every cell of the human body contains CoQ10. The mitochondria, the
area of cells where energy is produced, contain the most CoQ10. The heart and liver have the
greatest amount of CoQ10 because they contain the most mitochondria per cell. Most of us have
plenty of CoQ10 in our bodies until around the age of 30. About then, our bodies lose the
ability to manufacture it at the same levels, so the natural supply begins to diminish. This
important cardiovascular nutrient is thought to be essential for proper heart function.*1 2 It
is a powerful antioxidant that protects the body from free radicals.* It has
membrane-stabilizing properties shown to prevent the cellular damage that results from normal
metabolic processes.* As a coenzyme, this nutrient aids metabolic reactions, such as the
complex process of transforming food into ATP, the energy on which the body runs.*
CoQ10 may support the function of the heart by promoting energy production, supporting the
ability of the heart to contract, and providing powerful antioxidant protection.* The activity
of CoQ10 helps prevent the oxidization of LDL cholesterol, the 'bad' kind of cholesterol.
Because CoQ10 provides antioxidant protection, it helps prevent this oxidizing process, and in
so doing, it helps maintain cholesterol levels that are already within the normal range.* Also,
two studies report that CoQ10 promotes a greater ability to exercise.*3 4 And CoQ10 appears to
support the heart's function under varying levels of oxygen.*5 The heart is one of the few
organs in the body to function continuously without resting; therefore, the heart muscle
requires the highest level of energetic support. And any condition that causes a decrease in
CoQ10 could influence the energetic capacity of the heart, thus leaving the tissues more
susceptible to free radical attack.*6
L-Carnitine: Fuel for the Heart
L-Carnitine is an important amino acid involved in the metabolism and conversion of fatty acids
into energy for muscular activity.* While CoQ10 sparks the energy within the cells, L-carnitine
is like a shuttle, bringing fuel into heart cells to be burned as energy.* Carnitine has been
shown to support healthy heart function,*7 and is beneficial for optimizing endurance, muscle
strength and normal weight.*8 9 One six-month double blind trial found that L-carnitine
increased their exercise capacity by 26%.10 In animal studies and clinical experience,
L-carnitine has been shown to help maintain cholesterol levels already within the normal
range.*11
Hawthorn: Protects Blood Vessels
Hawthorn is a particularly rich source of a huge variety of bioflavonoids.* Bioflavonoids are
well recognized for their protective effects on blood vessels.* Hawthorn is also an especially
significant source of antioxidant anthocyanidins and cardiotonic amines.*12 Hawthorn berries
and flowers have a long history of use to help maintain heart health in different cultures.*
Due to its great complexity and extraordinary variety of heart-promoting, naturally-occurring
compounds, perhaps no other herbal extract has such potential for supporting healthy heart and
cardiovascular function as Hawthorn.*13 14 15 Studies suggest that Hawthorn supports
cardiovascular health in a variety of ways, including reducing cholesterol oxidation by
limiting free radical attack on LDL.*16 In addition, Hawthorn may help maintain blood
cholesterol levels already within normal ranges.*
Vitamin E: One of Your Heart's Best Friends
Vitamin E, a fat-soluble essential vitamin, belongs to an elite corps of age-defying nutrients
that easily earns blue-ribbon antioxidant status. Study after study has confirmed that vitamin
E acts like a loyal bodyguard as it promotes healthy cell membranes.* Vitamin E protects cells
from free radical oxidative stress, and therefore helps support the circulatory and
cardiovascular system.* According to a new federal survey, 30% of U.S. adults may not be
receiving the optimal level of Vitamin E, a condition that can influence the heart. Vitamin E
is available in CardiAll in the natural form which is 3-5x more potent than the synthetic form
(dl-alpha tocopherol), according to American Journal of Clinical Nutrition 65: 1997.* Vitamin E
also supports heart and blood vessel function because of its ability to neutralize the
oxidation of LDL cholesterol.* Vitamin E has also been shown to modulate oxidative DNA damage
from free radicals following exercise.*17
B-Vitamins, Folic Acid & Betaine: Nutritional Stars for Your Heart
Talk about your overnight sensations...recently, a once obscure B vitamin, Folic Acid (folate),
was hailed by mainstream medical researchers as a highly promising nutrient. Folic acid is
essential to the formation of red blood cells and aids in protein metabolism, however, prompted
by prior positive findings, the National Institutes of Health are funding further research into
the vitamin's potential benefits in supporting a healthy cardiovascular system. The U.S. FDA
has required that folic acid be added to enriched foods such as breads, flours, pastas, rice,
and breakfast cereals. In 1992 the U.S. Public Health Service doubled the RDA for folic acid
for women of childbearing age to 400 micrograms a day. The impetus for these changes came from
numerous studies linking folic acid levels to healthy heart function, and especially to
promoting healthy children at childbirth.*
A major 14-year study which appeared in the Journal of the American Medical Association (JAMA)
(Feb. 4, 1998) found that folic acid and B6 could significantly promote healthy heart
function.* Evidence from some 20 studies has revealed a previously unrecognized association
between a naturally occurring amino acid called homocysteine and heart health. Homocysteine is
an amino acid in your blood that can affect the cells lining the blood vessel walls.*18 Folic
acid helps maintain homocysteine levels already within the normal range, as do vitamins B6 and
B12.*19 20 Vitamin B6 serves a very important role of ensuring that biological processes,
including fat and protein metabolism take place, as they should.* Vitamin B12 plays a major
role in the metabolism of proteins, fats, and sugars, including the absorption and conversion
of folic acid into its active form.* One of most important functions of this vitamin is that it
helps to maintain the fatty sheath (myelin) that protects the nerves.*
Less than half of all Americans (12-40%) consume enough folic acid from foods, so leading heart
researchers recommend folic acid and B supplements. Of all the vitamins, folic acid absorption
is affected most by interaction with common drugs. Antacids, aspirin, alcohol and estrogen
replacement drugs all interfere with absorption of folic acid. Numerous studies have shown the
powerful effects B vitamins have on homocysteine. Users of vitamin preparations containing
these nutrients appeared to experience substantial support for cardiovascular and heart
function compared to nonusers.*21 In most cases, vitamin supplementation results in maintaining
already normal ranged plasma homocysteine.*22 23 Another important homocysteine-regulating
nutrient is Betaine, which is essential in recycling homocysteine back to methionine, and has
been shown to help maintain homocysteine levels already in the normal range.*24 25
Vitamin B1 (thiamine) aids in metabolism of carbohydrates, helps maintain the nervous system,
skin health and is involved with overall growth.* Vitamin B2 (riboflavin) is important for the
maintenance of healthy, supple skin and good vision.* It is one of the essential B vitamins
necessary for all sorts of chemical processes inside the body, such as converting food into
energy. Inositol HexaNiacinate is a flush-free form of Niacin and is important in promoting a
healthy nervous system, skin, and gastrointestinal functioning.*
Magnesium: Unsung Hero of Cardiovascular Health
Magnesium is essential for healthy heart function.* It's crucial to produce the high-energy
bonds that drive the energy machinery of your cells. More specifically, magnesium helps
maintain proper smooth muscle function in your blood vessels, helps shuttle potassium and
sodium into and out of cells maintaining proper membrane balance, and acts to maintain cardiac
conduction, heart muscle and vascular membranes.* It serves several crucial roles such as
assisting in the nerve and muscular impulses as well as muscular contraction.* Magnesium is
necessary for the metabolism of calcium, Vitamin C, phosphorus, sodium, and potassium.
Magnesium helps maintain stable heart muscle and vascular membranes. Factors that influence the
supply of Magnesium include: chronic emotional and mental stress, long-term use of diuretics,
alcohol abuse, prolonged use of antibiotics, malnourishment, and excessive use of some drugs,
such as Tagamet or Zantac. It is presented in CardiAll in its well-absorbed aspartate form.
Magnesium aspartate is particularly useful in this formula as it helps maintain blood
cholesterol levels already within the normal range, provides anti-fatigue effects, and
activates cellular metabolism.*26
Taurine: Supports Healthy Heart Function
Taurine is a sulfur-containing, membrane-stabilizing amino acid that is found in high
concentrations in muscle tissue. Physicians have used it for supporting healthy heart
function.*27 It functions in electrically active tissues such as the heart and brain to help
maintain stable cell membranes.* It also has functions in the blood vessels and appears to have
some antioxidant and detoxifying activity.* Taurine aids the movement of potassium, sodium,
calcium, and magnesium in and out of cells and thus helps support healthy nerve function.* It
comprises over 50% of the total free amino acid pool of the heart, and has been shown in some
studies to help maintain blood pressure and cholesterol levels already within the normal
ranges.*28 29
Carotenoids: Health Promoting Antioxidants
Antioxidant vitamins such as Beta-carotene have been hailed as lifesavers for their ability to
help protect our health and provide support for a healthy body. They neutralize free radicals
(the oxygen molecules that damage our body's cells). Carotenoids are acknowledged by the
leading heart health association in America to support healthy heart and blood vessel
function.*30 Beta carotene is an extremely important player in promoting heart health. More
than 200 studies have confirmed that foods rich in flavonoids, carotenoids and other
antioxidants provide support for a healthy cardiovascular function.* Consumption of fresh
fruits and vegetables has long been associated with promoting heart and eye health. If you eat
at least five to nine servings of fresh organic fruits and vegetables per day, you will, on
average, take in enough carotenoids to meet your body's needs. But it can be a challenge to
consume this many servings daily. That's why it makes sense to take out the additional
insurance in supplements. Each serving of CardiAll contains 5000 IU of natural mixed
carotenoids from Dunaliella.
Vitamin C: Still an All-Around Antioxidant Champ
Vitamin C is one of the best-known antioxidants, first made famous by the work of Linus
Pauling, two-time Nobel laureate who pioneered much of the research on its benefits. More
research has been done on vitamin C than any other nutrient. In addition to its wide-ranging
antioxidant talents, vitamin C promotes heart, immune and bone and joint health.* It also
promotes healthy blood-vessel linings and helps support already normal ranged levels of Lp(a),
a major factor in cardio health, while supporting the production of glutathione, another potent
antioxidant.*
Key Minerals: Zinc, Selenium, & Chromium for Health
Zinc is a trace mineral present in and indispensable to all forms of life. It is essential for
growth, pregnancy, and transmission of our genetic material.* Zinc is required as an enzyme
component in the eyes, liver, kidneys, muscles, skin, testes, and other organs. The highest
concentrations of zinc are in bones, the prostate gland, and the eyes. Selenium is a trace
mineral that is a structural element of the enzyme that protects glutathionine, which serves as
part of the body's internal defense against free radical damage. Selenium works hand in hand
with Vitamins C, E, and beta-carotene as an antioxidant defense. Chromium is a trace mineral
that is necessary for the proper functioning of insulin. Insulin plays a major role in the
metabolism of sugar and is involved in the body's use of protein and fat.
Turmeric: A Potent Spice for the Heart
Turmeric is an ancient spice dating back to the time of the Egyptian pharaohs. It is also a
traditional remedy in Ayurvedic medicine, an ancient Indian health system that dates back over
5,000 years. It has also been highly prized by Indo-Europeans, and today is generating a lot of
attention in the scientific community because of its many health-protective benefits. New
research shows this zesty spice, which puts the zing in curry sauces, may provide powerful
support for healthy heart and blood vessel function.* The key appears to lie in a compound
called Curcumin, which is found in turmeric. Curcumin provides broad-spectrum effects
throughout the body. In addition to being a potent antioxidant, Curcumin suppresses an enzyme
which is important for good health and overall comfort.* Turmeric's protective effects on the
cardiovascular system include helping to maintain cholesterol and triglyceride levels that are
already within the normal range, decreasing susceptibility of low density lipoprotein (LDL) to
lipid peroxidation,31 and promoting already normal platelet aggregation.*32 Curcumin may also
help support and maintain healthy joint function, flexibility, and mobility.*33 34 35 36 37
REFERENCES
1. Morisco C, Trimarco B, Condorelli M. Effect of coenzyme Q10: a long-term multicenter
randomized study. Clin Invest 1993;71:S134'36. 2. Mortensen SA, Vadhanavikit S, Baandrup U,
Folkers K. Long-term coenzyme Q10 therapy. Drug Exptl Clin Res 1985;11:581'93. 3. Kamikawa T,
Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance. Am J Cardiol
1985;56:247. 4. Mortensen SA. Perspectives on therapy with coenzyme Q10 (ubiquinone). Clin
Invest 1993;71:s116'23. 5. Tanaka J, Tominaga R, Yoshitoshi M, et al. Coenzyme Q10: the
prophylactic effect on low cardiac output following cardiac valve replacement. Ann Thorac Surg
1982;33:14551. 6. Molecular Aspects of Medicine, 1994, 15 Supplement 7. Dipalma JR. Carnitine
deficiency. Am Family Phys 1988;38:243-51. 8. Giamberardino MA et al. Effects of prolonged
L-carnitine administration on delayed muscle pain and CK release after eccentric effort. Int J
Sports Med 1996;17:320-4. 9. Kendler BS. Carnitine: an overview of its role in preventive
medicine. Prev Med 1986;15:373-90. 10. Mancini M, Rengo F, Lingetti M, Sorrentino GP, Nolfe G.
Controlled study on the therapeutic efficacy of propionyl-L-carnitine. Arzneimittelforschung
1992;42:1101'4. 11. Fujita T; Ando K; et al: Effects of increased adrenomedullary activity and
taurine in young patients with borderline hypertension. Circulation, 75(3):525-32 1987 Mar 12.
Cook N.C. & Samman S. 'Flavonoids-Chemistry, metabolism, cardioprotective effects, and dietary
sources' Nutritional Biochemistry 1996, 7:66-76. 13. Bahorun T, Trotin F, et al. Antioxidant
activities of Crataegus monogyna extracts. Planta Med 1994; 60:323-8. 14. Rewerski VW,
Piechoscki T, et al. Some pharmacological properties of oligomeric procyanidin isolated from
hawthorn (Crataegus oxyacantha). Arzneim-Forsch Drug Res 1967; 17:490-1. 15. Weikl A, Noh HS.
The influence of Crataegus on global cardiac insufficiency. Herz Gefabe 1993; 11:516-24. 16.
Rajendran S et al. Effects of tincture of Crataegus on the LDL receptor activity of hepatic
plasma membrane of rats fed an atherogenic diet. Atherosclerosis 1996;123:235-241. 17. Mutation
Research 346:1995 18. Circulation 97, Feb.10, 1998 19. American Journal of Clinical Nutrition
1998:68 20. Lancet 346, 1995 21. Graham IM, Daly LE, Refsum HM, Robinson K, Brattstrom LE,
Ueland PM, Palma-Reis RJ, et al. Plasma homocysteine. The European Concerted Action Project.
JAMA. 1997; 277(22):1775-81. 22. Ubbink JB, Vermaak WJH, van der Merwe A, Becker PJ, Delport R,
Potgieter HC. Vitamin requirements for the treatment of hyperhomocystinemia in humans. J Nutr.
1994; 124:1927-33. 23. Swift ME, Schultz TD. Relationship of vitamins B6 and B12 to
homocysteine levels. Nutr Rep Int. 1986; 34:1-14. 24. Betaine for Homocystinuria. The Medical
Letter. 1997; 39(993):12. 25. Boers GHJ. Hyperhomocystinemia: A Newly Recognized Risk Factor
For Vascular Disease. Netherlands Journal of Medicine. 1994; 45:34-41. 26. Gissen A.S.
'Magnesium and Health' Nutritional News July, 1993. 27. Bousquet P, Feldman J, Bloch R,
Schwartz J. Central cardiovascular effects of taurine: comparison with homotaurine and
muscimol. J Pharmacol Exp Ther 1981;219:213-218. 28. Fujita T, Ando K, Noda H, et al. Effects
of increased adrenomedullary activity and taurine. Circulation 1987;75:525'32. 29. Huxtable RJ
and Sebring LA. Cardiovascular actions of taurine. In: Kuriyama K, Huxtable R, Iwata H (eds.),
Sulfur Amino Acids: Biochemical and Clinical Aspects. New York:Alan R. Liss;1983:5-37. 30.
Better Nutrition, October 1997, 59:10, 48( 5). 31. Ramirez-Tortosa MC, Mesa MD, Aguilera MC, et
al. Oral administration of a turmeric extract inhibits LDL oxidation in rabbits.
Atherosclerosis 1999;147:371-378. 32. Srivastava R, Puri V, Srimal RC, Dhawan BN. Effect of
curcumin on platelet aggregation. Arzneim Forsch 1986;36:715-717. 33. Brouet I, Ohshima H.
Curcumin inhibits induction of nitric oxide synthetase in activated macrophages. Biochem
Biophys Res Commun 1995;206:533-540. 34. Chandra D, Gupta S. Arthritic activity of volatile oil
of Curcuma longa (Haldi). Ind J Med Res 1972;60:138-142. 35. Arora R, Basu N, Kapoor V, et al.
Studies on Curcuma longa (turmeric). Ind J Med Res 1971;59:1289-1295. 36. Mukhopadhyay A, Basu
N, Ghatak N, et al. Irritant activities of curcumin analogues in rats. Agents Actions
1982;12:508-515. 37. Srivastava R. Inhibition of neutrophil response by curcumin. Agents
Actions *These statements have not been evaluated by the Food and Drug Administration. This
product is not intended to diagnose, treat, cure, or prevent any disease.
Sale price: $21.30