  Alpha Lipoic Acid - 60 tab
DescriptionA universal antioxidant with key roles in energy and glucose metabolism. This unique antioxidant can neutralize free radicals just about everywhere in the body. It can also recharge other antioxidants, such as vitamins C, E, and glutathione. And, because it functions much like a B-vitamin, it helps convert food into energy. Studies show alpha-lipoic acid helps transport glucose into the cell thereby maintaining proper blood sugar metabolism. Although the body makes some alpha-lipoic acid, it might not be enough for optimal nutrition. Thus, dietary sources and/or supplements may be needed to fill in the gaps. Alpha-Lipoic Acid helps: * Deactivate free radicals * Extend the action of other antioxidants * Release energy from food * Maintain proper glucose metabolism. DirectionsOne tablet twice daily with meals, or as directed by
physician.Indications / UsesAlpha-lipoic acid is a nutritional coenzyme that is
involved in energy metabolism of proteins,
carbohydrates and fats, has physiological functions in
blood glucose disposal, and is able to scavenge a
number of free radicals.
Alpha-lipoic acid is a fat- and water-soluble, sulfurcontaining
coenzyme. It functions in the body much
like a B-vitamin, since it is involved in energy
production. As part of several multi-enzyme
complexes located in the mitochondria, alpha-lipoic
acid is essential for metabolizing carbohydrates,
proteins, and fats, and for the conversion of their
energy into ATP. Two of these enzyme complexes,
PDH (pyruvate dehydrogenase) and alpha-KGDH
(alpha-ketoglutarate dehydrogenase) are part of the
citric acid cycle (Krebs cycle), and as such assume a
central role for general energy production. Another
lipoic acid containing enzyme complex, BCKADH
(branched-chain keto-acid dehydrogenase), is
involved in deriving energy from the branched chain
amino acids, leucine, isoleucine, and valine.
A related metabolic function of alpha-lipoic acid is
its role in blood glucose disposal. This important
coenzyme appears to be necessary for the normal
transport of blood glucose into the cell. This may be
explained by its functions in the glucosemetabolizing
enzymes, PDH and alpha-KGDH, but
some researchers suspect a more direct role in
cellular glucose uptake at the cell membrane.
As early as 1959, alpha-lipoic acid was suggested to
be an antioxidant, since it could extend the actions of
vitamin C in guinea pigs, and those of vitamin E in
rats. It is only recently, however, that the specific
actions of alpha-lipoic acid in free radical quenching,
metal chelation, and antioxidant regeneration have
been investigated.
Body cells and tissues are threatened continuously by
damage caused by toxic free radicals and reactive
oxygen species (e.g., peroxides) which are produced
during normal oxygen metabolism, and by toxic
agents in the environment. Free radicals, once
formed, are capable of disrupting metabolic activity
and cell structure. When this occurs, additional free
radicals are produced which, in turn, can result in
more extensive damage to cells and tissues. The
uncontrolled production of free radicals is thought to
be a major contributing factor to many degenerative
diseases.
Alpha-lipoic acid is unique among biological
antioxidants, because it is soluble in both water and
lipids. This allows it to neutralize free radicals just
about everywhere in the body, inside and outside the
cells. Due to its unique sulfur-containing structure,
alpha-lipoic acid can scavenge several types of free
radicals, such as the highly reactive hydroxyl, and
singlet oxygen free radicals. It is also capable of
suppressing the generation of free radicals in the first
place, since alpha-lipoic acid chelates transition
metals, such as iron and copper. Because alphalipoic
acid is involved in so many different
antioxidant functions in virtually all body tissues, it
has been called the universal antioxidant.
Besides being a universal free radical scavenger,
alpha-lipoic acid can also recharge other antioxidant
systems throughout the body. As mentioned earlier,
it can extend the activity of vitamins C and E. In
addition, alpha-lipoic acid can also regenerate
glutathione.Product ContainsContent: Alpha-Lipoic Acid 100 mg.
|