5-HTP (5-hydroxytryptophan) is an intermediate metabolite between the amino acid L-tryptophan and serotonin; 5-HTP is serotonin’s immediate intracellular precursor. Serotonin is associated with positive mood and provides a substrate for the production of melatonin. 5-HTP is extracted from the bean of the African plant Griffonia simplicifolia, a natural vegetable source. L-Tyrosine is the amino acid precursor of the neurotransmitters dopamine and norepinephrine, both of which are important for the maintenance of a balanced mood. The combination of 5-HTP and L-Tyrosine, therefore, work together to beneficially support healthy brain neurochemistry.*
5-HTP, also known as 5-hydroxytryptophan, is an amino acid that is the direct precursor for serotonin, a brain neurotransmitter. The production of serotonin starts with tryptophan, which is converted into 5-HTP, and then into serotonin. Serotonin plays an important role in the regulation of appetite and mood and is also necessary for the production of melatonin. Melatonin is the main hormone responsible for the management of sleep.
5-HTP is extracted from the bean of the African plant Griffonia simplicifolia, a natural vegetable source. However, 5-HTP is not found in large amounts in the diet, and eating foods that contain tryptophan appears not to significantly increase 5-HTP levels.
Indications / Uses
As a dietary supplement, take 1 Vcap® daily, preferably on an empty stomach. For intensive use, take 1-2 Vcaps®, 1-2 times daily, under the supervision of a health care practitioner.
* Percent Daily Values are based on 2,000 calorie diet.
† Daily Value not established.
Cautions
Some individuals may initially experience nausea with 5-HTP, especially at higher doses. Reducing intake to no more than 50 mg three times daily and increasing intake slowly resolves this issue. Consult a physician if currently being treated or recently treated with an SSRI or an MAOI antidepressant.
L-Tyrosine is generally safe taken in low doses. However, overstimulation, restlessness, anxiety, insomnia, heart palpitations or arrhythmia are side effects that occur from higher doses or in sensitive individuals in as low a dose as 200 mg. L-Tyrosine may cause a severe increase in blood pressure in people taking MAOIs. There is some concern that L-Tyrosine might have additive effects with thyroid hormone medications. L-Tyrosine is a precursor to thyroid hormone and might boost levels. Interactions with L-dopa have been suggested.
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